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Dewcef-250 Injection
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Ceftriaxone 250 mg.
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Dewcef-500 Injection
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Ceftriaxone 500 mg.
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Dewcef-1Gm Injection
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Ceftriaxone 1 gm
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Dewcef-S-1.5 Gm
Injection
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Ceftriazone 1 gm.
Sulbactum 500 mg.
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Ceftriaxone (INN) (pronounced) is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to cefotaxime in terms of safety and efficacy. Ceftriaxone is often used (in combination, but not direct, with macrolide and/or aminoglycoside antibiotics) for the treatment of community-acquired or mild to moderate health care-associated pneumonia. It is also a choice drug for treatment of bacterial meningitis. In pediatrics, it is commonly used in febrile infants between 4 and 8 weeks of age who are admitted to the hospital to exclude sepsis. It has also been used in the treatment of Lyme disease and gonorrhea. The usual starting dose is 1 gram IV daily although dosage may be adjusted for body mass in younger patients. Doses range from 12 grams IV or IM every 12/24 hours, depending on the type and severity or the infection, up to 4 grams daily. For gonorrhoea the usual adult dose is a single intramuscular injection of 125 mg. Patients treated for gonorrhoea are usually also treated for chlamydia, often with azithromycin. Ceftriaxone is contraindicated in patients with known allergy to the cephalosporin class of antibiotics. It must not be mixed or administered simultaneously (within 48 hours) with calcium-containing solutions or products, even via different infusion lines (rare fatal cases of calcium-ceftriaxone precipitates in lung and kidneys in neonates have been described). Ceftriaxone may be reconstituted with 1% Lidocaine for injection when dose is to be given intramuscularly to prevent painful injection. Sulbactum is Betalactamase inhibitor.
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